713112-69-7
713112-69-7
Chemical Structure
SIC-19
- CAS No.: 713112-69-7
- Formula:C29H26N4O5S2
- Molecular Weight:574.67
InChIKey: DDRJMJOCSMOIBL-UHFFFAOYSA-N
SMILES: O=C(NC1=C(C(NNC(NC(C2=CC=CC=C2)=O)=S)=O)C(C3=CC=C(OC)C(OC)=C3)=C(C)S1)C4=CC=CC=C4
Biological Activity: SIC-19 is a SIK2 inhibitor and promotes SIK2 protein degradation via the ubiquitination pathway. SIC-19 inhibits cancer cell growth and sensitizes cells to PARP inhibitors (Such as Olaparib (HY-10162)), as well as in ovarian cancer organoids and xenograft models[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SIC-19 | 98.0% | SIC-19 is a SIK2 inhibitor and promotes SIK2 protein degradation via the ubiquitination pathway. SIC-19 inhibits cancer cell growth and sensitizes cells to PARP inhibitors (Such as Olaparib (HY-10162)), as well as in ovarian cancer organoids and xenograft models. | ||||||||||||||||||||
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References
Keywords
