748786-57-4
Chemical Structure
TLSC702
- CAS No.: 748786-57-4
- Formula:C18H15NO3S
- Molecular Weight:325.38
IUPAC Name: (Z)-3-(benzo[d]thiazol-2-yl)-4-(4-methoxyphenyl)but-3-enoic acid
InChIKey: SONSOTYJHQIJQV-RAXLEYEMSA-N
SMILES: O=C(O)CC(=CC1=CC=C(OC)C=C1)C2=NC=3C=CC=CC3S2
Biological Activity: TLSC702 is a human glyoxalase I (hGLO I) inhibitor with an IC50 of 2.0 μM. TLSC702 inhibits the activity of human glyoxalase I, thereby leading to the accumulation of methylglyoxal and its derived advanced glycation end products. TLSC702 inhibits tumor cell proliferation, induces apoptotic morphological changes, internucleosomal DNA fragmentation and PARP cleavage in tumor cells. TLSC702 can be used in research related to leukemia and lung cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TLSC702 | 95.61% | TLSC702 is a human glyoxalase I (hGLO I) inhibitor with an IC50 of 2.0 μM. TLSC702 inhibits the activity of human glyoxalase I, thereby leading to the accumulation of methylglyoxal and its derived advanced glycation end products. TLSC702 inhibits tumor cell proliferation, induces apoptotic morphological changes, internucleosomal DNA fragmentation and PARP cleavage in tumor cells. TLSC702 can be used in research related to leukemia and lung cancer. | ||||||||||||||||||||
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Keywords
