782485-03-4
![[Orn5]-URP Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-p1167.gif "[Orn5]-URP Chemical Structure")
782485-03-4
Chemical Structure
[Orn5]-URP
- CAS No.: 782485-03-4
- Formula:C48H62N10O10S2
- Molecular Weight:1003.20
SMILES: [ACFW-{Orn}-YCV (Disulfide bridge:Cys2-Cys7)]
Biological Activity: [Orn5]-URP is a potent and selective pure antagonist of Urotensin-II receptor (UT), with an pEC50 of 7.24. [Orn5]-URP displays no agonist activity[1][2].
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[Orn5]-URP | [Orn5]-URP is a potent and selective pure antagonist of Urotensin-II receptor (UT), with an pEC50 of 7.24. [Orn5]-URP displays no agonist activity. | |||||||||||||||||||||
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References
- [1]. Diallo M, et, al. [Orn5]URP acts as a pure antagonist of urotensinergic receptors in rat cortical astrocytes. Peptides. 2008 May; 29(5): 813-9. [Content Brief]
- [2]. David C, et, al. Structure-activity relationships and structural conformation of a novel urotensin II-related peptide. Peptides. 2004 Oct; 25(10): 1819-30. [Content Brief]
