79203-48-8
79203-48-8
Chemical Structure
7-Deacetylazadirone
- CAS No.: 79203-48-8
- Formula:C26H34O3
- Molecular Weight:394.55
InChIKey: CKDPEAINBFYEHJ-JDGKMSDRSA-N
SMILES: C[C@]12[C@@](CC[C@@]3(C2=CC[C@H]3C4=COC=C4)C)([H])[C@@]5([C@@](C(C)(C(C=C5)=O)C)([H])C[C@H]1O)C
Biological Activity: 7-Deacetylazadirone is an insect growth regulator targeting the ecdysone receptor (EcR), isolated from Teclea verdoorniana Exell. 7-Deacetylazadirone competitively binds insect EcR to block the activation of related signaling pathways, thereby disrupting insect metamorphosis and causing lethal molting. 7-Deacetylazadirone can be used in research on the development of green insecticides[1][2].
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7-Deacetylazadirone | 7-Deacetylazadirone is an insect growth regulator targeting the ecdysone receptor (EcR), isolated from Teclea verdoorniana Exell. 7-Deacetylazadirone competitively binds insect EcR to block the activation of related signaling pathways, thereby disrupting insect metamorphosis and causing lethal molting. 7-Deacetylazadirone can be used in research on the development of green insecticides. | |||||||||||||||||||||
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References
- [1]. Sivakumar S, et al. Comparative profiling of azadirachtin from Murraya koenigii, Azadirachta indica, and Curcuma longa: RP-HPLC analysis and mechanistic insights into ecdysone receptor molecular docking and dynamic studies. Results in Chemistry. 2026 Aug 11:103749.
- [2]. Ayafor JF, et al. Nkolbisine, a New Furoquinoline Alkaloid, and 7-Deacetylazadirone From Teclea verdoorniana. J Nat Prod. 1982;45(2):182-185.
