80047-24-1
80047-24-1
Chemical Structure
Win 47338
- CAS No.: 80047-24-1
- Formula:C12H11N3O2
- Molecular Weight:229.23
IUPAC Name: 6-hydroxy-2-methyl-[3,4'-bipyridine]-5-carboxamide
InChIKey: SWKVSFPUHCMFJY-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CC=NC=C2)=C(C)NC1=O)N
Biological Activity: Win 47338 (compound 14) is a control compound of inhibitors of the mitotic kinase monopolar spindle MPS1 and Aurora kinases (AurA/AurB) (Ki>100 μM)[1].
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Win 47338 | Win 47338 (compound 14) is a control compound of inhibitors of the mitotic kinase monopolar spindle MPS1 and Aurora kinases (AurA/AurB) (Ki>100 μM). | |||||||||||||||||||||
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References
- [1]. Fearon D, et al. Synthesis and profiling of a 3-aminopyridin-2-one-based kinase targeted fragment library: Identification of 3-amino-5-(pyridin-4-yl)pyridin-2(1H)-one scaffold for monopolar spindle 1 (MPS1) and Aurora kinases inhibition. Bioorg Med Chem. 2018 Jul 15;26(11):3021-3029. [Content Brief]
Keywords
