84687-42-3
Chemical Structure
Astragaloside III
- CAS No.: 84687-42-3
- Formula:C41H68O14
- Molecular Weight:784.97
IUPAC Name: (2S,3R,4S,5S,6R)-2-(((2S,3R,4S,5R)-2-(((2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-4,7-dihydroxy-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyltetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthren-9-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: FVFSMBDVZVUETN-BQAOMNQWSA-N
SMILES: O[C@@H]1[C@@H](O)[C@]([H])(O[C@@H]2[C@@H](O)[C@H](O)CO[C@]2(O[C@@H]3C(C)(C)[C@@]([C@@H](O)C[C@]4([H])[C@@]56CC[C@@]7(C)[C@@]4(C)C[C@H](O)[C@@]7([C@]8(C)O[C@H](C(C)(O)C)CC8)[H])([H])[C@]5(C6)CC3)[H])O[C@H](CO)[C@H]1O
Biological Activity: Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer[1][2][3][4][5].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Astragaloside III | 99.91% | Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer. | ||||||||||||||||||||
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Astragaloside III (Standard) | ≥98% | Astragaloside III (Standard) is the analytical standard of Astragaloside III (HY-N0434). This product is intended for research and analytical applications. Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer. | ||||||||||||||||||||
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References
- [1]. Indu P, et al. Antiviral activity of astragaloside II, astragaloside III and astragaloside IV compounds against dengue virus: Computational docking and in vitro studies. Microb Pathog. 2021 Mar;152:104563. [Content Brief]
- [2]. Chen X, et al. Astragaloside III Enhances Anti-Tumor Response of NK Cells by Elevating NKG2D and IFN-γ. Front Pharmacol. 2019 Aug 13;10:898. [Content Brief]
- [3]. Wang H, et al. Astragaloside III activates TACE/ADAM17-dependent anti-inflammatory and growth factor signaling in endothelial cells in a p38-dependent fashion. Phytother Res. 2020 May;34(5):1096-1107. [Content Brief]
- [4]. Wang S, et al. Astragaloside III from Astragalus membranaceus antagonizes breast cancer growth[J]. African Journal of Traditional, Complementary and Alternative Medicines, 2015, 12(3): 183-186.
- [5]. SHI Jing-chao, et al. Determination of Astragaloside III and Astragaloside IV in Astragalus with HPLC-ELSD Method. World Journal of Integrated Traditional and Western Medicine, 2014-07
