853003-48-2
853003-48-2
Chemical Structure
PF-00489791
Synonym(s): PF-489791
- CAS No.: 853003-48-2
- Formula:C20H28N8O4S
- Molecular Weight:476.55
IUPAC Name: 1-(2-ethoxyethyl)-5-(ethyl(methyl)amino)-7-((4-methylpyridin-2-yl)amino)-N-(methylsulfonyl)-1H-pyrazolo[4,3-d]pyrimidine-3-carboxamide
InChIKey: ZUHZNKJIJDAJFD-UHFFFAOYSA-N
SMILES: O=C(C1=NN(CCOCC)C2=C1N=C(N(CC)C)N=C2NC3=NC=CC(C)=C3)NS(=O)(C)=O
Biological Activity: PF-00489791 (PF-489791) is a potent inhibitor of phosphodiesterase 5A with IC50 of 1.5 nM. PF-00489791 can enhance the relaxation of blood vessels within the kidney and so reduce blood pressure, improving renal function[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-00489791 | 99.70% | PF-00489791 (PF-489791) is a potent inhibitor of phosphodiesterase 5A with IC50 of 1.5 nM. PF-00489791 can enhance the relaxation of blood vessels within the kidney and so reduce blood pressure, improving renal function. | ||||||||||||||||||||
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