859658-37-0
859658-37-0
Chemical Structure
AO65
- CAS No.: 859658-37-0
- Formula:C22H16BrNO6
- Molecular Weight:470.27
InChIKey: KXTNNBHRHWHLGG-UHFFFAOYSA-N
SMILES: BrC(C=C1)=CC=C1C2=COC3=CC(O4)=C(C=C32)C(C)=C(CC(NCC(O)=O)=O)C4=O
Biological Activity: AO65 is a TDP1 inhibitor (IC50 = 0.80 μM) that acts by inhibiting tyrosyl-DNA phosphodiesterase 1 to repair TOP1-mediated DNA damage. AO65 is used for TDP1-related DNA repair research[1].
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AO65 | AO65 is a TDP1 inhibitor (IC50 = 0.80 μM) that acts by inhibiting tyrosyl-DNA phosphodiesterase 1 to repair TOP1-mediated DNA damage. AO65 is used for TDP1-related DNA repair research. | |||||||||||||||||||||
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