862543-54-2
862543-54-2
Chemical Structure
Maropitant citrate
- CAS 番号: 862543-54-2
- Formula:C38H48N2O8
- Molecular Weight:660.80
IUPAC Name: (2S,3S)-2-benzhydryl-N-(5-(tert-butyl)-2-methoxybenzyl)quinuclidin-3-amine 2-hydroxypropane-1,2,3-tricarboxylate
InChIKey: XDZPFSKCXRGRIO-PNXDLZEOSA-N
SMILES: CC(C)(C)C1=CC=C(OC)C(CN[C@@H]2[C@H](C(C3=CC=CC=C3)C4=CC=CC=C4)N5CCC2CC5)=C1.O=C(CC(C(O)=O)(O)CC(O)=O)O
Biological Activity: Maropitant citrate is an orally active NK1 receptor antagonist. Maropitant citrate prevents vomiting and inhibits ulcerative dermatitis[1][2].
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Maropitant citrate | Maropitant citrate is an orally active NK1 receptor antagonist. Maropitant citrate prevents vomiting and inhibits ulcerative dermatitis. | |||||||||||||||||||||
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References
- [1]. Hay Kraus BL. Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs. J Am Vet Med Assoc. 2014 May 15;244(10):1164-9. [Content Brief]
- [2]. Williams-Fritze MJ, et al. Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background. J Am Assoc Lab Anim Sci. 2011 Mar;50(2):221-6. [Content Brief]
Keywords
