872113-12-7
872113-12-7
Chemical Structure
TCMDC-125457
- CAS No.: 872113-12-7
- Formula:C19H18ClN5O3
- Molecular Weight:399.83
IUPAC Name: N-(2-((5-chloro-2-methoxyphenyl)amino)-2-oxoethyl)-N-methyl-2-phenyl-2H-1,2,3-triazole-4-carboxamide
InChIKey: RHRZUZMCICRKJA-UHFFFAOYSA-N
SMILES: ClC1=CC(NC(CN(C(C2=NN(N=C2)C3=CC=CC=C3)=O)C)=O)=C(C=C1)OC
Biological Activity: TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
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TCMDC-125457 | TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites. | |||||||||||||||||||||
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Keywords
