88283-34-5
88283-34-5
Chemical Structure
11β-HSD1-IN-9
- CAS No.: 88283-34-5
- Formula:C13H9F3N2O
- Molecular Weight:266.22
IUPAC Name: 2-(pyrazin-2-yl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one
InChIKey: UFTKWWYMFSUYDJ-UHFFFAOYSA-N
SMILES: C1=C(C=CC(=C1)C(F)(F)F)C(=O)CC2=CN=CC=N2
Biological Activity: 11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment[1].
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11β-HSD1-IN-9 | 11β-HSD1-IN-9 (compound c4a) is a potent 11β-HSD1 inhibitor with IC50 values of 0.48 and 1.3 µM for human and murine 11β-HSD1, respectively. 11β-HSD1-IN-9 competitively interacts with rat 11β-HSD1. 11β-HSD1-IN-19 can be used in studies of obesity, hyperglycemia and cognitive impairment. | |||||||||||||||||||||
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