883956-47-6
883956-47-6
Chemical Structure
SRI-37240
- CAS No.: 883956-47-6
- Formula:C24H23N3O2
- Molecular Weight:385.46
IUPAC Name: 3-cyclohexyl-10-methyl-2-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione
InChIKey: VMNOIZKDWKJSPW-UHFFFAOYSA-N
SMILES: O=C1C2=C(N(C)C(N=C(N3C4CCCCC4)C5=CC=CC=C5)=C1C3=O)C=CC=C2
Biological Activity: SRI-37240 is a potent premature termination codons (PTCs) inhibitor. SRI-37240 suppresses CFTR nonsense mutations. SRI-37240 alters cellular translation termination at PTCs in HEK293T cells. SRI-37240 can also restore CFTR function in primary bronchial epithelial cells when combination with G418[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SRI-37240 | 98.29% | SRI-37240 is a potent premature termination codons (PTCs) inhibitor. SRI-37240 suppresses CFTR nonsense mutations. SRI-37240 alters cellular translation termination at PTCs in HEK293T cells. SRI-37240 can also restore CFTR function in primary bronchial epithelial cells when combination with G418. | ||||||||||||||||||||
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