88574-07-6
Chemical Structure
Fmoc-11-aminoundecanoic acid
- CAS No.: 88574-07-6
- Formula:C26H33NO4
- Molecular Weight:423.54
IUPAC Name: 11-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)undecanoic acid
InChIKey: IMEVDILDSCXKJW-UHFFFAOYSA-N
SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)NCCCCCCCCCCC(O)=O
Biological Activity: Fmoc-11-aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-11-aminoundecanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
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Fmoc-11-aminoundecanoic acid | Fmoc-11-aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-11-aminoundecanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | |||||||||||||||||||||
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