886209-60-5
886209-60-5
Chemical Structure
Cyclooctyne-O-PFP ester
- CAS No.: 886209-60-5
- Formula:C16H13F5O3
- Molecular Weight:348.26
IUPAC Name: perfluorophenyl 2-(cyclooct-2-yn-1-yloxy)acetate
InChIKey: FTKRNGMQMZGSDF-UHFFFAOYSA-N
SMILES: O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)COC2C#CCCCCC2
Biological Activity: Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cyclooctyne-O-PFP ester | Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Cyclooctyne-O-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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References
Keywords
