911715-90-7
911715-90-7
Chemical Structure
Rugocrixan
Synonym(s): AZD8797; KAND567
- CAS No.: 911715-90-7
- Formula:C19H25N5OS2
- Molecular Weight:403.56
IUPAC Name: (R)-2-((2-amino-5-(((S)-1-phenylethyl)thio)thiazolo[4,5-d]pyrimidin-7-yl)amino)-4-methylpentan-1-ol
InChIKey: ZMQSLMZOWVGBSM-GXTWGEPZSA-N
SMILES: CC(C)C[C@@H](NC1=NC(S[C@@H](C)C2=CC=CC=C2)=NC3=C1SC(N)=N3)CO
Biological Activity: AZD8797 (KAND567) is an allosteric non-competitive and orally active antagonist of the human CX3CR1 receptor; antagonizes CX3CR1 and CXCR2 with Kis of 3.9 and 2800 nM, respectively[1].
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Rugocrixan | 99.54% | AZD8797 (KAND567) is an allosteric non-competitive and orally active antagonist of the human CX3CR1 receptor; antagonizes CX3CR1 and CXCR2 with Kis of 3.9 and 2800 nM, respectively. | ||||||||||||||||||||
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References
Keywords
