915412-67-8
Chemical Structure
LP-261
- CAS No.: 915412-67-8
- Formula:C22H19N3O4S
- Molecular Weight:421.47
IUPAC Name: N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide
InChIKey: YUVDELGTFILMBB-UHFFFAOYSA-N
SMILES: CS(=O)(NC1=CC(C(C2=CC(OC)=NC=C2)=O)=CC(C3=CC=CC4=C3C=CN4)=C1)=O
Biological Activity: LP-261 is a potent and orally active anti-mitotic agent and shows an inhibition of in vitro tubulin polymerization with an EC50 of 3.2 μM[1]. LP-261 inhibits growth of a human non-small-cell lung tumor (NCI-H522) in vivo and can be used for cancer research[1].
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LP-261 | 99.94% | LP-261 is a potent and orally active anti-mitotic agent and shows an inhibition of in vitro tubulin polymerization with an EC50 of 3.2 μM. LP-261 inhibits growth of a human non-small-cell lung tumor (NCI-H522) in vivo and can be used for cancer research. | ||||||||||||||||||||
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Keywords