916742-11-5
Chemical Structure
JAK-IN-11
- CAS No.: 916742-11-5
- Formula:C23H22FN5O4S
- Molecular Weight:483.52
IUPAC Name: N-((5-((5-fluoro-4-((4-(prop-2-yn-1-yloxy)phenyl)amino)pyrimidin-2-yl)amino)-2-methylphenyl)sulfonyl)propionamide
InChIKey: IGLNXKVGKIFNBQ-UHFFFAOYSA-N
SMILES: C#CCOC1=CC=C(NC2=NC(NC3=CC=C(C)C(S(=O)(NC(CC)=O)=O)=C3)=NC=C2F)C=C1
Biological Activity: JAK-IN-11 (Example 1,II) is a potent and selective JAK inhibitor. JAK-IN-11 has the potential for the skin disorders (such as cutaneous lupus) treatment[1]. JAK-IN-11 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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JAK-IN-11 | 98.62% | JAK-IN-11 (Example 1,II) is a potent and selective JAK inhibitor. JAK-IN-11 has the potential for the skin disorders (such as cutaneous lupus) treatment. JAK-IN-11 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords
