918430-49-6
Chemical Structure
(Rac)-TTA-P2
Synonym(s): (Rac)-T-Type calcium channel inhibitor
- CAS No.: 918430-49-6
- Formula:C21H29Cl2FN2O2
- Molecular Weight:431.37
IUPAC Name: 3,5-dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide
InChIKey: DKNDOKIVCXTFHJ-UHFFFAOYSA-N
SMILES: O=C(NCC1(F)CCN(CC2CC(OCC2)(C)C)CC1)C3=CC(Cl)=CC(Cl)=C3
Biological Activity: (Rac)-TTA-P2 is the isomer of TTA-P2 (HY-10035), and can be used as an experimental control. TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease[1].
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(Rac)-TTA-P2 | 98.69% | (Rac)-TTA-P2 is the isomer of TTA-P2 (HY-10035), and can be used as an experimental control. TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease. | ||||||||||||||||||||
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Keywords
