92264-81-8

Hydroxybupropion Chemical Structure
92264-81-8

Chemical Structure

Hydroxybupropion

  • CAS No.: 92264-81-8
  • Formula:C13H18ClNO2
  • Molecular Weight:255.74

IUPAC Name: 1-(3-chlorophenyl)-2-((1-hydroxy-2-methylpropan-2-yl)amino)propan-1-one

InChIKey: AKOAEVOSDHIVFX-UHFFFAOYSA-N

SMILES: CC(NC(C)(C)CO)C(C1=CC=CC(Cl)=C1)=O

Biological Activity: Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion is metabolized by CYP2B6. Bupropion is an atypical antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake with an IC50 value of 1.7 μM. Hydroxybupropion is also a nACh receptor antagonist[1] .

Cat. No. Product Name Purity Description Pricing
HY-100637
Hydroxybupropion 99.91% Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion is metabolized by CYP2B6. Bupropion is an atypical antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake with an IC50 value of 1.7 μM. Hydroxybupropion is also a nACh receptor antagonist .
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