92264-81-8
Chemical Structure
Hydroxybupropion
- CAS No.: 92264-81-8
- Formula:C13H18ClNO2
- Molecular Weight:255.74
IUPAC Name: 1-(3-chlorophenyl)-2-((1-hydroxy-2-methylpropan-2-yl)amino)propan-1-one
InChIKey: AKOAEVOSDHIVFX-UHFFFAOYSA-N
SMILES: CC(NC(C)(C)CO)C(C1=CC=CC(Cl)=C1)=O
Biological Activity: Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion is metabolized by CYP2B6. Bupropion is an atypical antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake with an IC50 value of 1.7 μM. Hydroxybupropion is also a nACh receptor antagonist[1] .
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Hydroxybupropion | 99.91% | Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion is metabolized by CYP2B6. Bupropion is an atypical antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake with an IC50 value of 1.7 μM. Hydroxybupropion is also a nACh receptor antagonist . | ||||||||||||||||||||
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Keywords