924822-67-3
924822-67-3
Chemical Structure
MBTP-15324
- CAS No.: 924822-67-3
- Formula:C20H22N2O4S
- Molecular Weight:386.46
InChIKey: ANMCSJCVOHXCEF-UHFFFAOYSA-N
SMILES: CC1=CC=C(C(C(C(C2=CC=CS2)N3CCNCCO)=C(O)C3=O)=O)C=C1
Biological Activity: MBTP-15324 is an allosteric inhibitor of PRODH (human Kd = 1.45 μM). MBTP-15324 attenuates PRODH-mediated proline catabolism by binding to the Cavity1 pocket, inhibits the viability, colony formation, and migration of PRODH-overexpressing lung cancer cells, and reverses inflammation-, cell adhesion-, and ECM-related transcriptional programs. MBTP-15324 can be used for lung cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MBTP-15324 | MBTP-15324 is an allosteric inhibitor of PRODH (human Kd = 1.45 μM). MBTP-15324 attenuates PRODH-mediated proline catabolism by binding to the Cavity1 pocket, inhibits the viability, colony formation, and migration of PRODH-overexpressing lung cancer cells, and reverses inflammation-, cell adhesion-, and ECM-related transcriptional programs. MBTP-15324 can be used for lung cancer research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
