926664-32-6
926664-32-6
Chemical Structure
VRT-534
- CAS No.: 926664-32-6
- Formula:C25H24ClN3O4S
- Molecular Weight:497.99
InChIKey: OUGLISSDQZYBGK-ZHRRBRCNSA-N
SMILES: O=C(C1(C2=CC=C3C(OCO3)=C2)CC1)NC(S4)=NC=C4[C@@H](N(CC5)C[C@@H]5O)C(C=CC=C6)=C6Cl
Biological Activity: VRT-534 (Compound 3) is a chemical chaperone targeting connexin 26 (Cx26). Vrt-534 exhibits dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively. Vrt-534 can be used in research related to hearing impairment[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VRT-534 | 98.32% | VRT-534 (Compound 3) is a chemical chaperone targeting connexin 26 (Cx26). Vrt-534 exhibits dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively. Vrt-534 can be used in research related to hearing impairment. | ||||||||||||||||||||
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References
Keywords
