93117-07-8
93117-07-8
Chemical Structure
5-AIQ hydrochloride
Synonym(s): 5-Aminoisoquinolin-1-one hydrochloride
- CAS No.: 93117-07-8
- Formula:C9H9ClN2O
- Molecular Weight:196.63
IUPAC Name: 5-aminoisoquinolin-1(2H)-one hydrochloride
InChIKey: KWNLARCFSYAXLT-UHFFFAOYSA-N
SMILES: O=C1NC=CC2=C1C=CC=C2N.Cl
Biological Activity: 5-AIQ hydrochloride is a PARP-1 inhibitor. 5-AIQ hydrochloride is an important functional group in various drugs. 5-AIQ hydrochloride reduces the tissue injury associated with ischemia-reperfusion of the liver, it can be used for the research of the research conditions associated with ischemia-reperfusion of the liver[1][2].
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5-AIQ hydrochloride | 5-AIQ hydrochloride is a PARP-1 inhibitor. 5-AIQ hydrochloride is an important functional group in various drugs. 5-AIQ hydrochloride reduces the tissue injury associated with ischemia-reperfusion of the liver, it can be used for the research of the research conditions associated with ischemia-reperfusion of the liver. | |||||||||||||||||||||
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References
- [1]. Vinod KR, Chandra S, Sharma SK. Evaluation of 5-aminoisoquinoline (5-AIQ), a novel PARP-1 inhibitor for genotoxicity potential in vitro and in vivo. Toxicol Mech Methods. 2010 Feb;20(2):90-5. [Content Brief]
- [2]. Mota-Filipe H, et al. The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat. Med Sci Monit. 2002 Nov;8(11):BR444-53. [Content Brief]
