99390-76-8
Chemical Structure
BMY-27709
- CAS. Nr.: 99390-76-8
- Formula:C17H24ClN3O2
- Molecular Weight:337.84
IUPAC Name: 4-amino-5-chloro-2-hydroxy-N-((2S,6R,9aR)-6-methyloctahydro-2H-quinolizin-2-yl)benzamide
InChIKey: SQQXDSFKORQHET-GRYCIOLGSA-N
SMILES: C[C@H]1N2[C@@](CCC1)([H])C[C@H](CC2)NC(C3=C(C=C(C(Cl)=C3)N)O)=O
Biological Activity: BMY-27709 is an influenza virus growth inhibitor with an IC50 value of 3-8 μM against A/WSN/33 virus growth, and also exhibits inhibitory activity against some subtypes of influenza viruses. BMY-27709 acts early in the course of H1 and H2 virus infections, and exhibits antiviral activity through inhibition of hemagglutinin proteins. However, BMY-27709 has no effect on H3 subtype viruses and influenza B/Lee/40 viruses[1].
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BMY-27709 | BMY-27709 is an influenza virus growth inhibitor with an IC50 value of 3-8 μM against A/WSN/33 virus growth, and also exhibits inhibitory activity against some subtypes of influenza viruses. BMY-27709 acts early in the course of H1 and H2 virus infections, and exhibits antiviral activity through inhibition of hemagglutinin proteins. However, BMY-27709 has no effect on H3 subtype viruses and influenza B/Lee/40 viruses. | |||||||||||||||||||||
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