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Cat. No.: HY-168027

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CEP-1347-acid

CEP-1347-acid is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). CEP-1347-acid can be used for synthesis CEP1347-VHL-02 (HY-168026).

For research use only. We do not sell to patients.

Formula: C₃₀H₂₇N₃O₅S₂
Molecular Weight:573.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

CEP-1347-acid Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

CEP-1347-acid is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). CEP-1347-acid can be used for synthesis CEP1347-VHL-02 (HY-168026)^[1].

Chemical Information

Molecular Weight 573.68
Formula C₃₀H₂₇N₃O₅S₂
SMILES

CCSC1=CC2=C(C=C1)N([C@H]3O[C@@]4(C)[C@@](O)(C(O)=O)C3)C5=C2C(C(NC6)=O)=C6C7=C5N4C8=C7C=C(SCC)C=C8
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Karpińska K, et al. Selective Degradation of MLK3 by a Novel CEP1347-VHL-02 PROTAC Compound Limits the Oncogenic Potential of TNBC. J Med Chem. 2024 Sep 12;67(17):15012-15028. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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