ATS-9R
ATS-9R is a peptide consisting of an adipocyte-targeting sequence and D-form 9-arginine. ATS-9R selectively transfects mature adipocytes by binding to prohibitin. ATS-9R allows an adipocyte-targeted gene delivery in vitro and in vivo. ATS-9R can be used for the development of an adipocyte-targeted gene carrier. ATS-9R can be used for the study of obesity as well as obesity-induced metabolic syndromes.
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- Formel: C89H170N50O21S2
- Molecular Weight:2340.75
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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Molecular Weight 2340.75
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Formel C89H170N50O21S2
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Sequence
Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-d{Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg}-Cys (Disulfide bridge: Cys1-Cys18)
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Sequence Shortening
CKGGRAKD-d{RRRRRRRRR}-C (Disulfide bridge: Cys1-Cys18)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Yong-Hee Kim, et al. Adipocyte-targeting non-viral gene delivery system. US20160130579A1.
[2]. Won YW, et al. Oligopeptide complex for targeted non-viral gene delivery to adipocytes. Nat Mater. 2014 Dec;13(12):1157-64. [Content Brief]
[3]. Kolonin MG, et al. Reversal of obesity by targeted ablation of adipose tissue. Nat Med. 2004 Jun;10(6):625-32. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)