2138331-07-2
Chemical Structure
T2AA hydrochloride
- CAS. Nr.: 2138331-07-2
- Formula:C15H16ClI2NO3
- Molecular Weight:547.55
InChIKey: ILDRWUYIAXQKLH-PPHPATTJSA-N
SMILES: IC(C=C(C=C1I)C[C@H](N)CO)=C1OC2=CC=C(C=C2)O.Cl
Biological Activity: T2AA hydrochloride is a non-peptide small molecule PCNA inhibitor T2 amino alcohol (T2AA) that lacks thyroid hormone activity. T2AA hydrochloride inhibits the interaction of PCNA/PIP-box peptide (IC50=~1 μM) and the interaction of PCNA with full-length p21 protein[1].
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T2AA hydrochloride | T2AA hydrochloride is a non-peptide small molecule PCNA inhibitor T2 amino alcohol (T2AA) that lacks thyroid hormone activity. T2AA hydrochloride inhibits the interaction of PCNA/PIP-box peptide (IC50=~1 μM) and the interaction of PCNA with full-length p21 protein. | |||||||||||||||||||||
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Keywords