MLCK
The MLCK group encodes myosin light chain kinases, calcium/calmodulin-dependent enzymes dedicated to phosphorylating the regulatory light chain of myosin II on serine 19, stimulating actomyosin ATPase activity and contraction. The group spans the long smooth-muscle MLCK gene, which also produces non-muscle isoforms governing cell migration and endothelial barrier integrity, and dedicated skeletal and cardiac muscle paralogs that tune contraction kinetics in each tissue. Through regulatory light chain phosphorylation these kinases control vascular tone, epithelial permeability, cytokinesis, and cardiomyocyte contractility, and their inhibition or dysregulation affects hypertension, asthma, inflammatory edema, and heart disease.
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MLCK Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
