TKL-Unique
TKL-Unique gathers the diverse TKL-group enzymes that cannot be assigned to the IRAK, LRRK, MLK, RAF, RIPK, or STKR families. The branch mixes catalytically active serine/threonine kinases with pseudokinases such as the Tribbles proteins (TRIB1-3), which lack key catalytic residues and instead recruit the COP1 ubiquitin ligase to degrade substrates like C/EBP-alpha, regulating metabolism and myeloid leukemogenesis. Members act as node-like regulators of protein turnover, adhesion, vesicle trafficking, and stress signaling rather than as canonical cascade tiers. Their heterogeneity makes each a bespoke research target, and recombinant proteins support interaction and degradation-pathway studies.
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TKL-Unique Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
