New antiviral antibiotics, cycloviracins B1 and B2. II. Structure determination

  • J Antibiot (Tokyo). 1992 Sep;45(9):1472-80. doi: 10.7164/antibiotics.45.1472.
M Tsunakawa  1 ,  C Kotake ,  T Yamasaki ,  T Moriyama ,  M Konishi ,  T Oki
Affiliations
  • 1. Bristol-Myers Squibb Research Institute, Tokyo, Japan.
PMID: 1429233 DOI: 10.7164/antibiotics.45.1472
Abstract

The structures of novel antiviral Antibiotics, cycloviracins B1 and B2 have been determined by means of chemical and spectroscopic methods including 2D NMR correlation spectroscopy. The Antibiotics are unique macrocyclic diesters consisting of two D-glucoses, three 2-O-methyl-D-glucoses and two (C24 and C26) hydroxy fatty acids.

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