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Art. -Nr.: HY-184400

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Pynazolam

Pynazolam is a predicted positive allosteric modulator of GABA_A receptor. 3D-field QSAR and RVM models predict an IC₅₀ of approximately 0.40 nM. Pynazolam can be used in studies related to GABA_A receptor pharmacology.

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CAS. Nr.: 2034366-97-5
Formel: C₁₆H₁₂N₆O₂
Molecular Weight:320.31

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pynazolam Chemical Structure

CAS. Nr.: 2034366-97-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

GABA_A receptor

In Vitro

Pynazolam is predicted to be one of the most active designer benzodiazepines at the GABA-AR, with a log 1/c value of 9.4, indicating potent inhibitory activity in displacing [³H]-diazepam from rat cerebral cortex binding sites^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2034366-97-5
Molecular Weight 320.31
Formel C₁₆H₁₂N₆O₂
SMILES

O=[N+](C1=CC=C(N2C(CN=C3C4=NC=CC=C4)=NN=C2C)C3=C1)[O-]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Catalani V, et al. In silico studies on recreational drugs: 3D quantitative structure activity relationship prediction of classified and de novo designer benzodiazepines. Chemical biology & drug design. 2023 Jan;101(1):40-51. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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