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Art. -Nr.: HY-186208

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TACC3-IN-3

TACC3-IN-3 is a TACC3 inhibitor. TACC3 is a scaffold protein that is highly expressed in various tumors and regulates microtubule/centrosome stability via phosphorylation by Aurora A. TACC3-IN-3 inhibits the proliferation of triple-negative breast cancer cells. TACC3-IN-3 is applicable to triple-negative breast cancer research.\n

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CAS. Nr.: 3115244-67-9
Formel: C₂₅H₂₇N₅O
Molecular Weight:413.51

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

TACC3-IN-3 Chemical Structure

CAS. Nr.: 3115244-67-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
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- In Vitro
Chemical Information
Reinheit & Dokumentation
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Calculators
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Bioz

Biologische Aktivität

Beschreibung

Alle Aurora Kinase Isoform-spezifische Produkte anzeigen :

In Vitro

TACC3-IN-3 (Compound 65) inhibits the proliferation of CAL-51 cells after 72 h, with a GI₅₀ value of 0.31 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3115244-67-9
Molecular Weight 413.51
Formel C₂₅H₂₇N₅O
SMILES

CN1C2=CC=C(C=C2N=C1)C3=CC=NC(NC4=CC(N5C[C@H](O[C@H](C5)C)C)=CC=C4)=C3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Yang, et al. Tacc inhibitor compound, pharmaceutical composition, and preparation method therefor and use thereof. WO2026026956.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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TACC3-IN-3

Alle Aurora Kinase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

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TACC3-IN-3 Related Classifications

HY-186208 Related Classifications