Basivarsen linker
Basivarsen linker is a linker used in HY-177452 Zeleciment basivarsen for coupling a TfR1-binding Fab Zeleciment (HY-P990780) and an antisense oligonucleotide. Zeleciment basivarsen is an antibody-oligonucleotide conjugate (AOC) designed to target mutant nuclear myotonic dystrophy protein kinase (DMPK) RNA for RHase H-mediated degradation to correct splicing. It is used for the study of myotonic dystrophy type 1 (DM1).
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- CAS No.: 2763758-01-4
- Formule: C50H81N11O16
- Masse moléculaire:1092.24
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
IC50 & Target
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AOC Linkers |
Chemical Information
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CAS No. 2763758-01-4
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Masse moléculaire 1092.24
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Formule C50H81N11O16
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SMILES
NC(CCOCCOCCOCCOCCNC(OC[C@H]1[C@]2([H])[C@@]1([H])CCC3=C(N(N=N3)CCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC4=CC=C(C=C4)COC(N)=O)=O)=O)=O)CC2)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Basivarsen linker Related Classifications
HY-177454 Related Classifications
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