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Cat. No.: HY-137979

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Flunitrazolam

Name: Flunitrazolam
Brand: MedChemExpress
SKU: HY-137979
Price: 215.00 USD
Availability: PreOrder

(Synonyms: FNTZ)

Flunitrazolam (FNTZ) is an orally active triazolobenzodiazepine designer benzodiazepine compound and a positive allosteric modulator of the GABA_A receptor. Flunitrazolam undergoes biometabolic transformation, and 7-amino-flunitrazolam and 7-acetamido-flunitrazolam are its main detectable metabolites in urine. Flunitrazolam can be used in research related to GABA-mediated diseases, such as neurological disorders.

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CAS No.: 2243815-18-9
Formule: C₁₇H₁₂FN₅O₂
Masse moléculaire:337.31

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Flunitrazolam Chemical Structure

CAS No.: 2243815-18-9

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

In Vitro

Flunitrazolam (compound 36) acts as a positive allosteric modulator of α1β2γ2 GABA_A receptors in CHO cells, and its activity depends on the classical BZD α⁺/γ2^- binding pocket.^[1]
Flunitrazolam (FNTZ) undergoes biotransformation, and 7-amino-FNTZ and 7-acetamido-FNTZ are its main detectable metabolites in urine; moreover, in human liver microsomes, 7-amino-FNTZ is the only metabolite of flunitrazolam produced under the study conditions^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2243815-18-9
Appearance Solid
Masse moléculaire 337.31
Formule C₁₇H₁₂FN₅O₂
Color Light yellow to yellow
SMILES

O=[N+](C1=CC=C(N2C(CN=C3C4=CC=CC=C4F)=NN=C2C)C3=C1)[O-]
Synonyms

FNTZ
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (294 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Norman C, et al. In vitro γ-aminobutyric acid A (GABA) receptor activity and binding interactions at the α/γ interface of 53 prescription and designer benzodiazepines. Communications chemistry. 2026 Apr 07;9(1):155.

[2]. Ameline A, et al. Detection of the designer benzodiazepine flunitrazolam in urine and preliminary data on its metabolism. Drug testing and analysis. 2019 Feb;11(2):223-229.

[3]. Cornett EM, et al. New benzodiazepines for sedation. Best Practice & Research Clinical Anaesthesiology. 2018 Jun 1;32(2):149-64.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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