Bcas2 - BCAS2 pre-mRNA processing factor Gene

Also Known as 6430539P16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68183

Summary

Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing. Predicted to be located in centrosome and nuclear speck. Predicted to be part of DNA replication factor A complex; Prp19 complex; and U2-type catalytic step 2 spliceosome. Is expressed in several structures, including central nervous system; early conceptus; oocyte; peripheral nervous system ganglion; and submandibular gland primordium. Human ortholog(s) of this gene implicated in breast Cancer. Orthologous to human BCAS2 (BCAS2 pre-mRNA processing factor). [provided by Alliance of Genome Resources, Apr 2022]

Bcas2 Products (3)

mRNA Protein Name
NM_001356330.1 NP_001343259.1 pre-mRNA-splicing factor SPF27 isoform 2
NM_001356331.1 NP_001343260.1 pre-mRNA-splicing factor SPF27 isoform 3
NM_026602.4 NP_080878.2 pre-mRNA-splicing factor SPF27 isoform 1
Biological Process GO Annotation Evidence Références Source
acts upstream of or within alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
34972250 MGI
acts upstream of or within oocyte development IMP
IMP: Inferred from mutant phenotype
34972250 MGI
acts upstream of or within oogenesis IMP
IMP: Inferred from mutant phenotype
34972250 MGI
acts upstream of or within ovarian follicle development IMP
IMP: Inferred from mutant phenotype
34972250 MGI
acts upstream of or within protein catabolic process IMP
IMP: Inferred from mutant phenotype
34972250 MGI
acts upstream of or within spindle assembly IMP
IMP: Inferred from mutant phenotype
34972250 MGI
Cellular Component GO Annotation Evidence Références Source
part of Prp19 complex IMP
IMP: Inferred from mutant phenotype
34972250 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pre-mRNA-splicing factor SPF27

  • DNA amplified in mammary carcinoma 1 protein

  • breast carcinoma amplified sequence 2

  • breast carcinoma-amplified sequence 2 homolog

Orthologs Information

Species Symbol Source ID
Homo sapiens Bcas2 NCBI NCBI:10286