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Cat. No.: HY-153275A

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KM-001-E2

Name: KM-001-E2
Brand: MedChemExpress
SKU: HY-153275A
Price: 760.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (S)-KM-001)

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(S)-KM-001 ((S)-KM-001) is the enantiomer of KM-001 (HY-153275). KM-001 is a TRPV3 channel antagonist and can be used for studying skin itching and keratinosis diseases.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 99.08%
CAS No.: 2682864-43-1
Formule: C₂₆H₂₅FN₂O₂
Masse moléculaire:416.49

Stockage:

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

KM-001-E2 Chemical Structure

CAS No.: 2682864-43-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

(S)-KM-001 ((S)-KM-001) is the enantiomer of KM-001 (HY-153275). KM-001 is a TRPV3 channel antagonist and can be used for studying skin itching and keratinosis diseases^[1].

Chemical Information

CAS No. 2682864-43-1
Appearance Solid
Masse moléculaire 416.49
Formule C₂₆H₂₅FN₂O₂
Color White to off-white
SMILES

OCC1=C([C@H]2CN(CC2)C(C3=CC=C(C=N3)F)=O)C=CC(C4=C(C5CC5)C=CC=C4)=C1
Synonyms

(S)-KM-001
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Barak SL, et al. 629 Evaluating the safety and efficacy of topical KM-001, a TRPV3 inhibitor, for treatment of pruritus in patients with Lichen Simplex Chronicus (LSC): a first in human, double-blind, randomized vehicle-controlled study. Journal of Investigative Dermatology. 2023 May 1;143(5):S108.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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