Choline Chloride-13C3
Based on 2 publication(s) in Google Scholar
Choline Chloride-13C3 is the 13C-labeled Choline chloride (HY-B1337). Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma.
For research use only. We do not sell to patients.
- Purity : 98.06%
- Formula: C213C3H14ClNO
- Molecular Weight:142.60
-
Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications Citing Use of MedChemExpress (MCE) Choline Chloride-13C3
MoreAll Histamine Receptor Isoforms
More
Biological Activity
Description
IC50 & Target
|
Human Endogenous Metabolite |
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled CAS 67-48-1
-
Appearance Solid
-
Molecular Weight 142.60
-
Formula C213C3H14ClNO
-
Color White to off-white
-
SMILES
OCC[N+]([13CH3])([13CH3])[13CH3].[Cl-]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
Nat Cell Biol
Differentiation, ageing and leukaemia alter the metabolic profile of human bone marrow haematopoietic stem and progenitor cells. [Abstract]2025 Aug;27(8):1367-1380. PMID: 40664811 -
Solvent & Solubility
In Vitro:
DMSO : ≥ 140 mg/mL (981.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 60 mg/mL (420.76 mM; Need ultrasonic)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 7.0126 mL | 35.0631 mL | 70.1262 mL | 175.3156 mL |
| 5 mM | 1.4025 mL | 7.0126 mL | 14.0252 mL | 35.0631 mL | |
| 10 mM | 0.7013 mL | 3.5063 mL | 7.0126 mL | 17.5316 mL | |
| 15 mM | 0.4675 mL | 2.3375 mL | 4.6751 mL | 11.6877 mL | |
| 20 mM | 0.3506 mL | 1.7532 mL | 3.5063 mL | 8.7658 mL | |
| 25 mM | 0.2805 mL | 1.4025 mL | 2.8050 mL | 7.0126 mL | |
| 30 mM | 0.2338 mL | 1.1688 mL | 2.3375 mL | 5.8439 mL | |
| 40 mM | 0.1753 mL | 0.8766 mL | 1.7532 mL | 4.3829 mL | |
| 50 mM | 0.1403 mL | 0.7013 mL | 1.4025 mL | 3.5063 mL | |
| 60 mM | 0.1169 mL | 0.5844 mL | 1.1688 mL | 2.9219 mL | |
| 80 mM | 0.0877 mL | 0.4383 mL | 0.8766 mL | 2.1914 mL | |
| 100 mM | 0.0701 mL | 0.3506 mL | 0.7013 mL | 1.7532 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.