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Cat. No.: HY-184887

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Chrysoeriol 7-O-neohesperidoside

Chrysoeriol 7-O-neohesperidoside is a flavonoid glycoside with cytotoxicity against cancer cells. Chrysoeriol 7-O-neohesperidoside can be used in cancer-related research such as cervical cancer and liver cancer.

For research use only. We do not sell to patients.

CAS No.: 111133-90-5
Formula: C₂₈H₃₂O₁₅
Molecular Weight:608.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Chrysoeriol 7-O-neohesperidoside Chemical Structure

CAS No.: 111133-90-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

Chrysoeriol 7-O-neohesperidoside (compound 4) (5.2-50 μM; 48 h) inhibits proliferation of Hep2, HepG2, MCF7, and HeLa human tumor cell lines in vitro, with the most potent activity against Hep2 cells (IC₅₀ = 37.8 μM) and weaker activity against HepG2 (IC₅₀ = 57.9 μM), MCF7 (IC₅₀ = 71.9 μM), and HeLa (IC₅₀ = 75.2 μM) cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

Hep2 (epidermal carcinoma of larynx), HeLa (cervical carcinoma), HepG2 (liver carcinoma), MCF7 (breast carcinoma)
Concentration:

5.2, 20.5, 41, 50 μM
Incubation Time:

48 h
Result:

Exhibited antiproliferative activity against all four tested cell lines, with varying potency.
Showed moderate activity against the Hep2 cell line, with an IC₅₀ of 37.8 μM.
Had weaker activity against HepG2, MCF7, and HeLa cell lines, with IC₅₀ values of 57.9 μM, 71.9 μM, and 75.2 μM, respectively.

Chemical Information

CAS No. 111133-90-5
Molecular Weight 608.55
Formula C₂₈H₃₂O₁₅
SMILES

O=C1C=2C(OC(=C1)C3=CC(OC)=C(O)C=C3)=CC(O[C@H]4[C@H](O[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@@H](CO)O4)=CC2O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Farid M, et al. Phytochemical constituents of the butanol fraction of Arum palaestinum Boiss: Cytotoxic and antiviral screening. Journal of Materials and Environmental Sciences, 2017, 8(7):2585-2591.

[2]. Cruz J E R D, et al. Evaluation of the Antioxidant, Antimicrobial, and Anti-Biofilm Effects of the Stem Bark, Leaf, and Seed Extracts from Hymenaea courbaril and Characterization by UPLC-ESI-QTOF-MS/MS Analysis. Antibiotics, 2023, 12(11): 1601.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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