Clodinafop-propargyl-13C6
Clodinafop-propargyl-13C6 is the 13C-labeled Clodinafop-propargyl (HY-136380). Clodinafop-propargyl, an aryloxyphenoxy-propionate herbicide, is used for postemergence control of annual grasses in cereals. Clodinafop-propargyl has organ toxicity and developmental toxicity.
For research use only. We do not sell to patients.
- Formula: C1113C6H13ClFNO4
- Molecular Weight:355.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 105512-06-9
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Molecular Weight 355.70
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Formula C1113C6H13ClFNO4
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SMILES
C[C@@H](O[13C]1=[13CH][13CH]=[13C](OC2=NC=C(Cl)C=C2F)[13CH]=[13CH]1)C(OCC#C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Reproductive and Developmental Toxicity Study
Reproductive and developmental toxicity studies detect adverse effects of prenatal or peri/postnatal exposure on maternal condition, pregnancy maintenance, embryo-fetal survival, fetal growth, structural development, and offspring reproductive or developmental endpoints; classic rat protocols generate readouts by comparing treated groups with vehicle, pair-fed, or untreated controls for implantation, resorption, fetal weight, crown-rump length, external morphology, visceral morphology, skeletal ossification, anogenital distance, nipple/areola retention, and postnatal cohort outcomes.
Purity & Documentation
References
[1]. Wenbi Guan, et al. Dissipation of clodinafop-propargyl and its metabolite in wheat field ecosystem. Bull Environ Contam Toxicol. 2013 Jun;90(6):750-5. [Content Brief]
[3]. European Food Safety Authority (EFSA), et al. Peer review of the pesticide risk assessment of the active substance clodinafop (variant evaluated clodinafop-propargyl). EFSA J. 2020;18(7):e06151. Published 2020 Jul 7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Clodinafop-propargyl-13C6 Related Classifications
HY-136380S Related Classifications
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