hCAIX-IN-19
hCAIX-IN-19 is a sulfonamides inhibitor against hCA IX with an inhibition constant (KI ) of 6.2 nM and show good selectivity over hCA I (hCA I/ hCA IX = 117).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C29H34N4O4S2
- Molecular Weight:566.73
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
|
hCA IX 6.2 nM (Ki) |
In Vitro
hCAIX-IN-19 (1.0-100.0 μM, 48 h ) shows antiproliferative activity in U87MG cells, MDA-MB-231 cells and PANC-1 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
-
Cell Line:U87MG cells, MDA-MB-231 cells, PANC-1 cells
-
Concentration:1.0 μM, 3.0 μM, 10.0 μM, 30.0 μM, 100.0 μM
-
Incubation Time:48 h
-
Result:Obviously affected cell proliferation at 100 μM in U87MG cells.
Reduced cell proliferation to 39% at the highest dose tested in MDA-MB-231 cells.
Chemical Information
-
Molecular Weight 566.73
-
Formel C29H34N4O4S2
-
SMILES
O=C1N[C@@]2([H])[C@@](CS[C@H]2CCCCC(N(CC3=CC=C(C=CC=C4)C4=C3)CCC5=CC=C(S(=O)(N)=O)C=C5)=O)([H])N1
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
hCAIX-IN-19 Related Classifications
HY-157135 Related Classifications
Powered by Bioz