JB-95
Based on 1 Customer Validation
JB-95, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 can selectively disrupt the outer membrane but not the inner membrane of E. coli.
For research use only. We do not sell to patients.
- Purity: 98.03%
- CAS No.: 1873323-60-4
- Formula: C92H151N35O14
- Molecular Weight:1971.41
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 1873323-60-4
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Appearance Solid
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Molecular Weight 1971.41
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Formula C92H151N35O14
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Color White to off-white
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Sequence
cyclo-(Trp-Arg-Ile-Arg-Ile-{d-Arg}-Trp-Lys-Arg-Leu-Arg-Arg-{d-Pro}-Pro)
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Sequence Shortening
cyclo-(WRIRI-{d-Arg}-WKRLRR-{d-Pro}-P)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (50.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (286 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5073 mL | 2.5363 mL | 5.0725 mL | 12.6813 mL |
| 5 mM | 0.1015 mL | 0.5073 mL | 1.0145 mL | 2.5363 mL | |
| 10 mM | 0.0507 mL | 0.2536 mL | 0.5073 mL | 1.2681 mL | |
| 15 mM | 0.0338 mL | 0.1691 mL | 0.3382 mL | 0.8454 mL | |
| 20 mM | 0.0254 mL | 0.1268 mL | 0.2536 mL | 0.6341 mL | |
| 25 mM | 0.0203 mL | 0.1015 mL | 0.2029 mL | 0.5073 mL | |
| 30 mM | 0.0169 mL | 0.0845 mL | 0.1691 mL | 0.4227 mL | |
| 40 mM | 0.0127 mL | 0.0634 mL | 0.1268 mL | 0.3170 mL | |
| 50 mM | 0.0101 mL | 0.0507 mL | 0.1015 mL | 0.2536 mL |