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Cat. No.: HY-186079B

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Deethyl-emvistegrast TFA

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Based on 1 Customer Validation

Deethyl-emvistegrast TFA is a quinoline derivative and also a α4β7 integrin inhibitor. Deethyl-emvistegrast TFA is the hydrolytic product of Emvistegrast (HY-177080). Deethyl-emvistegrast TFA modulates inflammatory pathways. Deethyl-emvistegrast TFA can be used in research related to inflammatory bowel disease (Crohn's disease and ulcerative colitis).

For research use only. We do not sell to patients.

Purity: 98.96%
Formula: C₃₅H₂₉F₇N₆O₈
Molecular Weight:794.63

Storage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Deethyl-emvistegrast TFA Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Integrin Isoforms :

Chemical Information

Appearance Solid
Molecular Weight 794.63
Formula C₃₅H₂₉F₇N₆O₈
Color Light yellow to yellow
SMILES

CN1C2=C(C=CN=C2)C(N(C1=O)C3=C(N=CC=C4)C4=C(C[C@H](NC(C5=C(F)C=C(N6CCOC[C@@H]6C(F)(F)F)C=C5C)=O)C(O)=O)C=C3)=O.OC(C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. BLOMGREN, Peter A., et al. International application published under the patent cooperation treaty (PCT). WO 2020/092375 A1, 07 May 2020.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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Biological Activity
- Description
Chemical Information
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References

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Deethyl-emvistegrast TFA

MCE Bioactive Compound Library

All Integrin Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Deethyl-emvistegrast TFA Related Classifications

HY-186079B Related Classifications