1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Dihydroisopimaric acid

Dihydroisopimaric acid activates large conductance Ca2+ activated K+ (BK) channels alphabeta1 in the direct measurement of BKalphabeta1 opening under whole-cell voltage clamp.

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Dihydroisopimaric acid Chemical Structure

Dihydroisopimaric acid Chemical Structure

CAS No. : 5673-36-9

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Description

Dihydroisopimaric acid activates large conductance Ca2+ activated K+ (BK) channels alphabeta1 in the direct measurement of BKalphabeta1 opening under whole-cell voltage clamp[1].

In Vitro

Effects of these compounds (10 microM) on the membrane potential of HEKBKalphabeta1 were monitored by use of DiBAC(4)(3), a voltage-sensitive dye. Dihydroisopimaric acid induces substantial membrane hyperpolarization. Dihydroisopimaric acid (1-10 microM) activates BKalphabeta1 in the direct measurement of BKalphabeta1 opening under whole-cell voltage clamp[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

304.47

Formula

C20H32O2

CAS No.
SMILES

O=C([C@]1(C)CCC[C@]2(C)[C@@]3([H])CC[C@](C)(CC)CC3=CC[C@@]12[H])O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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References
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Dihydroisopimaric acid Related Classifications

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Product Name:
Dihydroisopimaric acid
Cat. No.:
HY-133614
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