Dimethyl sulfoxide, cryoprotectant vitrification agent
Based on 1 publication(s) in Google Scholar
Dimethyl sulfoxide, cryoprotectant vitrification agent (DMSO, cryoprotectant vitrification agent) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. This product has been sterilized and has no endotoxin. It can be used for long-term cell cryopreservation and will not affect the normal growth of cells.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 67-68-5
- Formula: C2H6OS
- Molecular Weight:78.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Dimethyl sulfoxide, cryoprotectant vitrification agent
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Erythroleukemia cell line | IC50 |
280 mM
Compound: DMSO
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Anticancer activity against mouse Erythroleukemia cell line assessed as inhibition of cell growth
Anticancer activity against mouse Erythroleukemia cell line assessed as inhibition of cell growth
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[PMID: 34591474] |
| HEK293 | IC50 |
232 μM
Compound: DMSO
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Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay
Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay
|
[PMID: 27108400] |
| HL-60 | IC50 |
108 μM
Compound: DMSO
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Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 27108400] |
| LN-18 | IC50 |
223 μM
Compound: DMSO
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Antiproliferative activity against human LN18 cells after 48 hrs by MTT assay
Antiproliferative activity against human LN18 cells after 48 hrs by MTT assay
|
[PMID: 27108400] |
| MDCK-II | GI50 |
123 μM
Compound: DMSO
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Growth inhibition of MDCK2 cells after 72 hrs by MTT assay
Growth inhibition of MDCK2 cells after 72 hrs by MTT assay
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[PMID: 32787102] |
| MDCK-II | GI50 |
137 μM
Compound: DMSO
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Growth inhibition of MDCK2 cells over expressing human ABCG2 after 72 hrs by MTT assay
Growth inhibition of MDCK2 cells over expressing human ABCG2 after 72 hrs by MTT assay
|
[PMID: 32787102] |
| THP-1 | IC50 |
119 μM
Compound: DMSO
|
Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay
Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay
|
[PMID: 27108400] |
DMSO is an organic solvent that is freely miscible with water, lipids and organic agents. These properties allow for exceptional membrane penetration. The mechanism of action of DMSO is thought to be a combination of anti-inflammatory effects, nerve blockade, smooth muscle relaxation, and collagen inhibition[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 67-68-5
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Appearance Liquid (Density: 1.1 g/cm3)
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Molecular Weight 78.13
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Formula C2H6OS
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Color Colorless to light yellow
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SMILES
O=S(C)C
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Synonyms
DMSO, cryoprotectant vitrification agent; Dimethyl sulfoxide vitrification agent
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Ecotoxicol Environ Saf
Uncovering the effects of ATBC plasticizers on intracerebral hemorrhage outcomes based on network toxicology and in vitro and in vivo experimental validation. [Abstract]2025 Jul 15:300:118486. PMID: 40482445
Purity & Documentation
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Data Sheet (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)