Dimethyldioctadecylammonium bromide
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Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 3700-67-2
- Formula: C38H80BrN
- Molecular Weight:630.95
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
In Vitro
Dimethyldioctadecylammonium (bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 3700-67-2
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Appearance Solid
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Molecular Weight 630.95
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Formula C38H80BrN
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCCCCC[N+](C)(CCCCCCCCCCCCCCCCCC)C.[Br-]
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Synonyms
Dioctadecyldimethylammonium bromide; DODAB
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
Ethanol : 100 mg/mL (158.49 mM; Need ultrasonic)
DMSO : 2 mg/mL (3.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (245 KB)
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SDS (459 KB)
- English - EN (459 KB)
- Français - FR (459 KB)
- Deutsch - DE (459 KB)
- Norwegian - NO (459 KB)
- Español - ES (459 KB)
- Swedish - SV (459 KB)
- Italian - IT (459 KB)
- Korean - KR (459 KB)
- Portuguese - PT (459 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol | 1 mM | 1.5849 mL | 7.9246 mL | 15.8491 mL | 39.6228 mL |
| Ethanol | 5 mM | 0.3170 mL | 1.5849 mL | 3.1698 mL | 7.9246 mL |
| 10 mM | 0.1585 mL | 0.7925 mL | 1.5849 mL | 3.9623 mL | |
| 15 mM | 0.1057 mL | 0.5283 mL | 1.0566 mL | 2.6415 mL | |
| 20 mM | 0.0792 mL | 0.3962 mL | 0.7925 mL | 1.9811 mL | |
| 25 mM | 0.0634 mL | 0.3170 mL | 0.6340 mL | 1.5849 mL | |
| 30 mM | 0.0528 mL | 0.2642 mL | 0.5283 mL | 1.3208 mL | |
| 40 mM | 0.0396 mL | 0.1981 mL | 0.3962 mL | 0.9906 mL | |
| 50 mM | 0.0317 mL | 0.1585 mL | 0.3170 mL | 0.7925 mL | |
| 60 mM | 0.0264 mL | 0.1321 mL | 0.2642 mL | 0.6604 mL | |
| 80 mM | 0.0198 mL | 0.0991 mL | 0.1981 mL | 0.4953 mL | |
| 100 mM | 0.0158 mL | 0.0792 mL | 0.1585 mL | 0.3962 mL |