Diploicin
Diploicin is a diphenyl ether lactone compound with anti-gram-positive bacteria activity, which is found in lichens.
For research use only. We do not sell to patients.
- CAS No.: 527-93-5
- Formula: C16H10Cl4O5
- Molecular Weight:424.06
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
4 μM
Compound: 2
|
Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay
Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay
|
[PMID: 19919064] |
| HaCaT | IC50 |
>10 μM
Compound: 2
|
Cytotoxicity against human HaCaT cells after 72 hrs by MTT assay
Cytotoxicity against human HaCaT cells after 72 hrs by MTT assay
|
[PMID: 19919064] |
Chemical Information
-
CAS No. 527-93-5
-
Molecular Weight 424.06
-
Formula C16H10Cl4O5
-
SMILES
O=C1OC2=C(C(OC)=C(C(C)=C2OC3=C(C(O)=C(C(C)=C13)Cl)Cl)Cl)Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Diploicin Related Classifications
HY-W704321 Related Classifications
Powered by Bioz