DMAB-anabaseine dihydrochloride
DMAB-anabaseine dihydrochloride is a selective nicotinic α7 receptor partial agonist and an α4β2 nAChR antagonist. DMAB-anabaseine dihydrochloride shows cognition-enhancing effects.
For research use only. We do not sell to patients.
- CAS No.: 154149-38-9
- Formula: C19H23Cl2N3
- Molecular Weight:364.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (aged 22-24 months)[2]
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Dosage:2 mg/kg
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Administration:i.p.; daily; for 30 days
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Result:Enhanced reference memory in 17-arm radial maze testing.
Chemical Information
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CAS No. 154149-38-9
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Molecular Weight 364.31
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Formula C19H23Cl2N3
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SMILES
CN(C)C(C=C1)=CC=C1/C=C2C(C3=CN=CC=C3)=NCCC/2.[H]Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. K E Stevens, et al. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl). 1998 Apr;136(4):320-7. [Content Brief]
[2]. G W Arendash, et al. Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21. Brain Res. 1995 Mar 20;674(2):252-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)