DMAB-anabaseine dihydrochloride

Name: DMAB-anabaseine dihydrochloride
Brand: MedChemExpress
SKU: HY-107671
Rating: 4.5 (0 reviews)

Cat. No.: HY-107671: Ficha de datos Instrucciones de manejo
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DMAB-anabaseine dihydrochloride is a selective nicotinic α7 receptor partial agonist and an α4β2 nAChR antagonist. DMAB-anabaseine dihydrochloride shows cognition-enhancing effects.

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DMAB-anabaseine dihydrochloride Estructura química

No. CAS : 154149-38-9

Tamaño	Stock	Cantidad
1 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
25 mg	Obtener un presupuesto 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto
100 mg	Obtener un presupuesto

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Descripciòn

DMAB-anabaseine dihydrochloride is a selective nicotinic α7 receptor partial agonist and an α4β2 nAChR antagonist. DMAB-anabaseine dihydrochloride shows cognition-enhancing effects^[1]^[2].

In Vivo

DMAB-anabaseine dihydrochloride (2 mg/kg; i.p.; daily; for 30 days) shows cognition-enhancing effects and improves long-term memory in rats^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male Sprague-Dawley rats (aged 22-24 months)^[2]
Dosage:	2 mg/kg
Administration:	i.p.; daily; for 30 days
Result:	Enhanced reference memory in 17-arm radial maze testing.

Peso molecular

364.31

Fòrmula

C₁₉H₂₃Cl₂N₃

No. CAS

154149-38-9

SMILES

CN(C)C(C=C1)=CC=C1/C=C2C(C3=CN=CC=C3)=NCCC/2.[H]Cl.[H]Cl

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. K E Stevens, et al. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl). 1998 Apr;136(4):320-7. [Content Brief]

[2]. G W Arendash, et al. Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21. Brain Res. 1995 Mar 20;674(2):252-9. [Content Brief]