154149-38-9
154149-38-9
Chemical Structure
DMAB-anabaseine dihydrochloride
- CAS No.: 154149-38-9
- Formula:C19H23Cl2N3
- Molecular Weight:364.31
IUPAC Name: (E)-4-((5,6-dihydro-[2,3'-bipyridin]-3(4H)-ylidene)methyl)-N,N-dimethylaniline dihydrochloride
InChIKey: DHCNEWWWKHBASC-YNHPUKFJSA-N
SMILES: CN(C)C(C=C1)=CC=C1/C=C2C(C3=CN=CC=C3)=NCCC/2.[H]Cl.[H]Cl
Biological Activity: DMAB-anabaseine dihydrochloride is a selective nicotinic α7 receptor partial agonist and an α4β2 nAChR antagonist. DMAB-anabaseine dihydrochloride shows cognition-enhancing effects[1][2].
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DMAB-anabaseine dihydrochloride | DMAB-anabaseine dihydrochloride is a selective nicotinic α7 receptor partial agonist and an α4β2 nAChR antagonist. DMAB-anabaseine dihydrochloride shows cognition-enhancing effects. | |||||||||||||||||||||
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References
- [1]. K E Stevens, et al. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl). 1998 Apr;136(4):320-7. [Content Brief]
- [2]. G W Arendash, et al. Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21. Brain Res. 1995 Mar 20;674(2):252-9. [Content Brief]
Keywords
