2. Metabolic Enzyme/Protease
  3. Oxidative Phosphorylation Mitochondrial Metabolism
  4. DX3-234

DX3-234 is an oxidative phosphorylation (OXPHOS) inhibitor. DX3-234 shows significant tumor suppression in the Pan02 syngeneic model of pancreatic cancer.

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DX3-234

DX3-234 화학구조

CAS No. : 2941323-59-5

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1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
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500 mg   견적 받기  

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DX3-234 Related Antibodies

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제품 설명

DX3-234 is an oxidative phosphorylation (OXPHOS) inhibitor. DX3-234 shows significant tumor suppression in the Pan02 syngeneic model of pancreatic cancer[1].

Cellular Effect
Cell Line Type Value Description References
MIA PaCa-2 IC50
0.02 μM
Compound: 64; DX3-234
Cytotoxicity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 3 days in glucose-containing medium by MTT assay
Cytotoxicity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 3 days in glucose-containing medium by MTT assay
[PMID: 34982568]
MIA PaCa-2 IC50
0.07 μM
Compound: 64; DX3-234
Cytotoxicity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 7 days in glucose-containing medium by MTT assay
Cytotoxicity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 7 days in glucose-containing medium by MTT assay
[PMID: 34982568]
MIA PaCa-2 IC50
42.6 nM
Compound: 64; DX3-234
Inhibition of oxidative phosphorylation in human MIA PaCa-2 cells assessed as reduction in ATP production incubated for 24 hrs in galactose-containing medium by CellTiter-glo luminescence assay
Inhibition of oxidative phosphorylation in human MIA PaCa-2 cells assessed as reduction in ATP production incubated for 24 hrs in galactose-containing medium by CellTiter-glo luminescence assay
[PMID: 34982568]
MIA PaCa-2 IC50
> 10 μM
Compound: 64; DX3-234
Cytotoxicity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 3 days in galactose-containing medium by MTT assay
Cytotoxicity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 3 days in galactose-containing medium by MTT assay
[PMID: 34982568]
분자량

565.71

화학식

C25H35N5O6S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC=C(C=C1)S(=O)(N2C[C@@H](CCC2)C(N3CCN(CC3)C4=NC(C(C)C)=NO4)=O)=O)(C5CCC5)=O
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
순도&문서
References
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DX3-234 Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DX3-2342941323-59-5Oxidative PhosphorylationMitochondrial Metabolismoxidative phosphorylationPan02syngeneicpancreatic cancer modelaerobic metabolismInhibitorinhibitorinhibit

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상품명:
DX3-234
Cat. No.:
HY-145306
수량:
MCE Japan Authorized Agent:

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