1. PROTAC
  2. Ligands for E3 Ligase
  3. E3 ligase Ligand 32

E3 ligase Ligand 32 (First product in Example 52) is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 32 can be connected to the ligand for protein by a linker to form PROTACs and can be used for the synthesis of PROTAC SMARCA2/4-degrader-29 (HY-162743).

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E3 ligase Ligand 32 Chemical Structure

E3 ligase Ligand 32 Chemical Structure

CAS No. : 2300099-98-1

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Description

E3 ligase Ligand 32 (First product in Example 52) is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 32 can be connected to the ligand for protein by a linker to form PROTACs and can be used for the synthesis of PROTAC SMARCA2/4-degrader-29 (HY-162743)[1].

Molecular Weight

338.16

Formula

C13H12BrN3O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1NC(=O)C(CC1)N2C3=C(C=C(Br)C=C3)N(C)C2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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E3 ligase Ligand 32 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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E3 ligase Ligand 32
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HY-W382038
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