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Cat. No.: HY-181799

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EG35

EG35 is a nucleotide-binding domain-targeted DnaK inhibitor. EG35 binds to Escherichia coli DnaK and inhibits the ATPase activity stimulated by DnaJ and GrpE.

For research use only. We do not sell to patients.

CAS No.: 2061310-68-5
Formula: C₃₆H₃₈F₂N₄O₃
Molecular Weight:612.71

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

EG35 Chemical Structure

CAS No.: 2061310-68-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

EG35 is a nucleotide-binding domain-targeted DnaK inhibitor. EG35 binds to Escherichia coli DnaK and inhibits the ATPase activity stimulated by DnaJ and GrpE^[1].

In Vitro

EG35 (50-200 μM) inhibits the ATPase activity of E. coli DnaK^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2061310-68-5
Molecular Weight 612.71
Formula C₃₆H₃₈F₂N₄O₃
SMILES

CN1CCN(CCOC2=C(CC3=CC(C1=O)=CC=C3)C=C(C=C2)C4=CN=C(C=C4)F)CC5(CCN(CC5)C6=CC=CC=C6F)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Feng Z, et al. ProMol_Func: A Structure-Free Deep Learning Model for Virtual Screening[J]. JACS Au, 2026.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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